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This study compares differentiable physics and PINN frameworks for reconstructing wall shear stress from passive scalar fields in cardiovascular flows, showing that hard-constraint PDE optimization outperforms soft-constraint neural networks when near-wall data is unavailable. The work advances the application of inverse problems in fluid dynamics by demonstrating how measurement location fundamentally impacts reconstruction fidelity using AI-augmented physics models.
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Wall Shear Stress Reconstruction from Concentration: Differentiable Physics and Physics-Informed Neural Networks

arXiv3 min read

arXiv:2606.06313v2 Announce Type: replace-cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients. Passive scalar fields, such as concentration or temperature, are advected by the same underlying velocity field and have the potential to uncover hidden flow physics metrics such as WSS. In this work, we demonstrate such reconstruction from spatially limited passive scalar observations using two fundamentally different inverse frameworks: a differentiable physics framework based on discrete adjoint, PDE-constrained optimization, which enforces the governing equations as hard constraints, and physics-informed neural networks (PINNs), which treat them as soft constraints. Benchmark problems include a 2D canonical backward-facing step (2D-BFS) and a 3D patient-specific stenotic coronary artery. For the 2D-BFS case, evaluated under three measurement scenarios (near-wall, far-field, and combined), PINN achieves high accuracy when near-wall data are available but fails when restricted to far-field measurements, whereas the differentiable physics approach recovers accurate WSS across all scenarios. In the 3D patient-specific case, the differentiable physics framework outperforms PINNs, yielding accurate WSS reconstruction. These results establish that measurement location and inverse formulation jointly determine reconstruction fidelity in scalar-based near-wall flow inference. The proposed framework opens a path toward estimation of near-wall hemodynamics from scalar transport data, with broader applicability to fluid flow problems where passive scalars can be observed.

Abstract:Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients. Passive scalar fields, such as concentration or temperature, are advected by the same underlying velocity field and have the potential to uncover hidden flow physics metrics such as WSS. In this work, we demonstrate such reconstruction from spatially limited passive scalar observations using two fundamentally different inverse frameworks: a differentiable physics framework based on discrete adjoint, PDE-constrained optimization, which enforces the governing equations as hard constraints, and physics-informed neural networks (PINNs), which treat them as soft constraints. Benchmark problems include a 2D canonical backward-facing step (2D-BFS) and a 3D patient-specific stenotic coronary artery. For the 2D-BFS case, evaluated under three measurement scenarios (near-wall, far-field, and combined), PINN achieves high accuracy when near-wall data are available but fails when restricted to far-field measurements, whereas the differentiable physics approach recovers accurate WSS across all scenarios. In the 3D patient-specific case, the differentiable physics framework outperforms PINNs, yielding accurate WSS reconstruction. These results establish that measurement location and inverse formulation jointly determine reconstruction fidelity in scalar-based near-wall flow inference. The proposed framework opens a path toward estimation of near-wall hemodynamics from scalar transport data, with broader applicability to fluid flow problems where passive scalars can be observed.

Fluid Dynamics (physics.flu-dyn); Machine Learning (cs.LG); Computational Physics (physics.comp-ph)

arXiv:2606.06313 [physics.flu-dyn]

(or arXiv:2606.06313v2 [physics.flu-dyn] for this version)

https://doi.org/10.48550/arXiv.2606.06313 Focus to learn more arXiv-issued DOI via DataCite

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Full text under the publisher's open licence · 326 words

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