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Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring. This skill provides research-backed thresholds from binder design competitions and published benchmarks.

Install

npx skills add adaptyvbio/protein-design-skills --skill protein-qc -a claude-code

Installs to .claude/skills/protein-qc/ · Each command fetches the skill straight from GitHub with the open skills CLI.

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Byte-identical to the scanned commit, with the repository’s licence and a SOURCE.txt.

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Why 80

Security100
Provenance67
Maintenance70
Licence100
Adoption38

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