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Poisson-model peak caller for ChIP-seq/ATAC-seq BAMs. MACS3 callpeak finds enriched regions (TF sites or histone marks) vs input/IgG; outputs BED narrowPeak/broadPeak for motif analysis, annotation, and differential binding. Use narrow peaks for TF ChIP-seq and ATAC-seq; broad for H3K27me3, H3K9me3, and other broad marks.

Install

npx skills add jaechang-hits/SciAgent-Skills --skill macs3-peak-calling -a claude-code

Installs to .claude/skills/macs3-peak-calling/ · Each command fetches the skill straight from GitHub with the open skills CLI.

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