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This research introduces PULSE, a self-supervised pretraining framework for physiological time series that leverages dynamical system structures to isolate shared system parameters from sample-specific noise. By theoretically grounding the extraction of generative variables, the method improves label efficiency and transfer learning capabilities across diverse real-world datasets. The approach offers a robust alternative to heuristic strategies, providing a principled way to enhance representation learning in medical signal processing.
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Self-Supervised Dynamical System Representations for Physiological Time-Series

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arXiv:2512.00239v2 Announce Type: replace Abstract: The effectiveness of self-supervised learning (SSL) for physiological time series depends on the ability of a pretraining objective to preserve information about the underlying physiological state while filtering out unrelated noise. However, existing strategies are limited due to reliance on heuristic principles or poorly constrained generative tasks. To address this limitation, we propose a pretraining framework that exploits the information structure of a dynamical systems generative model across multiple time-series. This framework reveals our key insight that class identity can be efficiently captured by extracting information about the generative variables related to the system parameters shared across similar time series samples, while noise unique to individual samples should be discarded. Building on this insight, we propose PULSE, a cross-reconstruction-based pretraining objective for physiological time series datasets that explicitly extracts system information while discarding non-transferrable sample-specific ones. We establish theory that provides sufficient conditions for the system information to be recovered, and empirically validate it using a synthetic dynamical systems experiment. Furthermore, we apply our method to diverse real-world datasets, demonstrating that PULSE learns representations that can broadly distinguish semantic classes, increase label efficiency, and improve transfer learning.

Abstract:The effectiveness of self-supervised learning (SSL) for physiological time series depends on the ability of a pretraining objective to preserve information about the underlying physiological state while filtering out unrelated noise. However, existing strategies are limited due to reliance on heuristic principles or poorly constrained generative tasks. To address this limitation, we propose a pretraining framework that exploits the information structure of a dynamical systems generative model across multiple time-series. This framework reveals our key insight that class identity can be efficiently captured by extracting information about the generative variables related to the system parameters shared across similar time series samples, while noise unique to individual samples should be discarded. Building on this insight, we propose PULSE, a cross-reconstruction-based pretraining objective for physiological time series datasets that explicitly extracts system information while discarding non-transferrable sample-specific ones. We establish theory that provides sufficient conditions for the system information to be recovered, and empirically validate it using a synthetic dynamical systems experiment. Furthermore, we apply our method to diverse real-world datasets, demonstrating that PULSE learns representations that can broadly distinguish semantic classes, increase label efficiency, and improve transfer learning.

Machine Learning (cs.LG); Machine Learning (stat.ML)

arXiv:2512.00239 [cs.LG]

(or arXiv:2512.00239v2 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2512.00239 Focus to learn more arXiv-issued DOI via DataCite

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