snpeff-variant-annotation
From the author
Annotate and filter VCF variants with SnpEff and SnpSift. SnpEff predicts functional effects (HIGH/MODERATE/LOW/MODIFIER), genes, transcripts, AA changes, HGVS; SnpSift filters and adds ClinVar/dbSNP. Java CLI with Python subprocess integration. Use ANNOVAR for multi-database annotation; Ensembl VEP for REST API; SnpEff for fast CLI with pre-built genomes.
Install
npx skills add jaechang-hits/SciAgent-Skills --skill snpeff-variant-annotation -a claude-code
Installs to .claude/skills/snpeff-variant-annotation/ · Each command fetches the skill straight from GitHub with the open skills CLI.
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