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This research provides critical mathematical evidence that standard multi-agent network architectures can catastrophically amplify semantic drift and hallucinations in clinical diagnostic settings, directly threatening patient safety. By demonstrating how structural bottlenecks force systems into entropy saturation where ground truth is overwritten, the study establishes topological stability as a non-negotiable requirement for reliable autonomous medical AI.
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Spectral Dynamics of Semantic Drift in Clinical Multi-Agent Language Model Networks

arXiv3 min read

arXiv:2607.22758v1 Announce Type: cross Abstract: The integration of iterative LLMs within multi-agent diagnostic frameworks requires a rigorous quantitative reevaluation of underlying communication topologies. Frequently used architectural paradigms depend on scale-free or small-world networks, assuming optimal communication efficiency. Our study mathematically dismantles that assumption for semantic data. By mapping multi-agent communication uncertainty trajectories onto a 768-dimensional Bio_ClinicalBERT embedding space via an analytical isotropic variance proxy using Barab'asi--Albert (BA) and Watts--Strogatz (WS) networks, we prove that structural bottlenecks compromise diagnostic safety. Our phase transition matrices illustrate that localized dense cliques confine hallucinated data, preventing global consensus and forcing the system toward a permanent entropy saturation threshold of $H_{\infty} \approx 5.947$. As a result, we measure a severe terminal cosine similarity degradation of 53.29%, completely overwriting the original ground-truth. Moreover, the terminal semantic drift reveals a catastrophic variance amplification of 51.81% ($\rho = 1.5181$) in highly clustered architectures, proving total system unpredictability when compared to Erd\H{o}s--R'enyi configurations ($\rho = 1.0766$). Instead of reducing errors, hub-centric systems autonomously compound localized hallucinations. By introducing dynamic spectral monitoring operating at an $\mathcal{O}(N^3)$ time complexity and imposing a strict lower bound on algebraic connectivity ($\lambda_{2_{min}}$) via the continuous eigen-decomposition of the graph Laplacian, we present a mathematically rigorous technique to ensure global state diffusion. Securing the reliability of autonomous medical diagnostics necessitates treating topological stability as a non-negotiable quantitative imperative.

Abstract:The integration of iterative LLMs within multi-agent diagnostic frameworks requires a rigorous quantitative reevaluation of underlying communication topologies. Frequently used architectural paradigms depend on scale-free or small-world networks, assuming optimal communication efficiency. Our study mathematically dismantles that assumption for semantic data. By mapping multi-agent communication uncertainty trajectories onto a 768-dimensional Bio_ClinicalBERT embedding space via an analytical isotropic variance proxy using Barab'asi--Albert (BA) and Watts--Strogatz (WS) networks, we prove that structural bottlenecks compromise diagnostic safety. Our phase transition matrices illustrate that localized dense cliques confine hallucinated data, preventing global consensus and forcing the system toward a permanent entropy saturation threshold of $H_{\infty} \approx 5.947$. As a result, we measure a severe terminal cosine similarity degradation of 53.29%, completely overwriting the original ground-truth. Moreover, the terminal semantic drift reveals a catastrophic variance amplification of 51.81% ($\rho = 1.5181$) in highly clustered architectures, proving total system unpredictability when compared to Erdős--R'enyi configurations ($\rho = 1.0766$). Instead of reducing errors, hub-centric systems autonomously compound localized hallucinations. By introducing dynamic spectral monitoring operating at an $\mathcal{O}(N^3)$ time complexity and imposing a strict lower bound on algebraic connectivity ($\lambda_{2_{min}}$) via the continuous eigen-decomposition of the graph Laplacian, we present a mathematically rigorous technique to ensure global state diffusion. Securing the reliability of autonomous medical diagnostics necessitates treating topological stability as a non-negotiable quantitative imperative.

Multiagent Systems (cs.MA); Artificial Intelligence (cs.AI)

arXiv:2607.22758 [cs.MA]

(or arXiv:2607.22758v1 [cs.MA] for this version)

https://doi.org/10.48550/arXiv.2607.22758 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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Full text under the publisher's open licence · 315 words

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