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This research addresses critical competency gaps in frontier models by introducing Universal Report Generation (UniRG), a framework that uses reinforcement learning to optimize medical imaging report generation directly against clinical metrics. By moving beyond supervised fine-tuning prone to overfitting, UniRG achieves superior generalization across diverse institutions and sets new state-of-the-art benchmarks on the ReXrank dataset for chest X-ray analysis. The work demonstrates how RL can unify multimodal reasoning capabilities specifically tailored for high-value biomedicine applications rather than generic text tasks.
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Scaling medical imaging report generation with multimodal reinforcement learning

arXiv2 min read

arXiv:2601.17151v2 Announce Type: replace-cross Abstract: Frontier models have demonstrated remarkable capabilities in understanding and reasoning with natural-language text, but they still exhibit major competency gaps in multimodal understanding and reasoning especially in high-value verticals such as biomedicine. Medical imaging report generation is a prominent example. Supervised fine-tuning can substantially improve performance, but they are prone to overfitting to superficial boilerplate patterns. In this paper, we introduce Universal Report Generation (UniRG) as a general framework for medical imaging report generation. By leveraging reinforcement learning as a unifying mechanism to directly optimize for evaluation metrics designed for end applications, UniRG can significantly improve upon supervised fine-tuning and attain durable generalization across diverse institutions and clinical practices. We trained UniRG-CXR on publicly available chest X-ray (CXR) data and conducted a thorough evaluation in CXR report generation with rigorous evaluation scenarios. On the authoritative ReXrank benchmark, UniRG-CXR sets new overall SOTA, outperforming prior state of the art by a wide margin. We release our model at https://huggingface.co/microsoft/UniRG-CXR.

Abstract:Frontier models have demonstrated remarkable capabilities in understanding and reasoning with natural-language text, but they still exhibit major competency gaps in multimodal understanding and reasoning especially in high-value verticals such as biomedicine. Medical imaging report generation is a prominent example. Supervised fine-tuning can substantially improve performance, but they are prone to overfitting to superficial boilerplate patterns. In this paper, we introduce Universal Report Generation (UniRG) as a general framework for medical imaging report generation. By leveraging reinforcement learning as a unifying mechanism to directly optimize for evaluation metrics designed for end applications, UniRG can significantly improve upon supervised fine-tuning and attain durable generalization across diverse institutions and clinical practices. We trained UniRG-CXR on publicly available chest X-ray (CXR) data and conducted a thorough evaluation in CXR report generation with rigorous evaluation scenarios. On the authoritative ReXrank benchmark, UniRG-CXR sets new overall SOTA, outperforming prior state of the art by a wide margin. We release our model at this https URL.

Computer Vision and Pattern Recognition (cs.CV); Computation and Language (cs.CL)

arXiv:2601.17151 [cs.CV]

(or arXiv:2601.17151v2 [cs.CV] for this version)

Full text under the publisher's open licence · 178 words

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