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SafeECGMatch introduces a semi-supervised learning framework that addresses label scarcity in ECG classification by dynamically aligning model confidence with empirical accuracy to handle out-of-distribution data. By jointly optimizing time-frequency representations, the method enables trustworthy rejection of anomalies while improving reliability on standard physiological benchmarks like PTB-XL. This approach advances safe knowledge discovery for medical AI without relying on large-scale labeled datasets.
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SafeECGMatch: Calibration-Aware Joint Frequency and Time Space Semi-Supervised Learning for Open-Set ECG Classification

arXiv2 min read

arXiv:2606.08037v2 Announce Type: replace-cross Abstract: Electrocardiogram (ECG) classification models often suffer from severe label scarcity, making semi-supervised learning (SSL) an attractive strategy for reducing annotation costs. In clinical settings, however, unlabeled pools frequently contain out-of-distribution (OOD) anomalies or diagnostic groups absent from the labeled set. Standard SSL forces incorrect pseudo-labels onto these unseen classes, producing overconfident predictions. To address this, we propose SafeECGMatch, a calibration-aware safe SSL framework for single-label ECG classification under label distribution mismatch. Methodologically, SafeECGMatch employs a dual-branch architecture extracting time-frequency latent representations via ECG-specific augmentations. Crucially, it dynamically aligns confidence with empirical accuracy through adaptive label smoothing and temperature scaling, calibrating both the multiclass classifier and the OOD detector across temporal and spectral domains. This joint optimization allows trustworthy OOD rejection and reliable pseudo-labeling. Evaluated on the PTB-XL and PhysioNet/CinC Challenge benchmarks, SafeECGMatch achieves state-of-the-art accuracy and calibration, advancing reliable knowledge discovery in physiological time-series. Code is available at https://github.com/labhai/SafeECGMatch.

Abstract:Electrocardiogram (ECG) classification models often suffer from severe label scarcity, making semi-supervised learning (SSL) an attractive strategy for reducing annotation costs. In clinical settings, however, unlabeled pools frequently contain out-of-distribution (OOD) anomalies or diagnostic groups absent from the labeled set. Standard SSL forces incorrect pseudo-labels onto these unseen classes, producing overconfident predictions. To address this, we propose SafeECGMatch, a calibration-aware safe SSL framework for single-label ECG classification under label distribution mismatch. Methodologically, SafeECGMatch employs a dual-branch architecture extracting time-frequency latent representations via ECG-specific augmentations. Crucially, it dynamically aligns confidence with empirical accuracy through adaptive label smoothing and temperature scaling, calibrating both the multiclass classifier and the OOD detector across temporal and spectral domains. This joint optimization allows trustworthy OOD rejection and reliable pseudo-labeling. Evaluated on the PTB-XL and PhysioNet/CinC Challenge benchmarks, SafeECGMatch achieves state-of-the-art accuracy and calibration, advancing reliable knowledge discovery in physiological time-series. Code is available at this https URL.

8 pages. Accepted to the KDD 2026 - UC (The 32nd ACM SIGKDD Conference on Knowledge Discovery and Data Mining - Undergraduate Consortium)

Machine Learning (cs.LG); Artificial Intelligence (cs.AI)

arXiv:2606.08037 [cs.LG]

(or arXiv:2606.08037v2 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2606.08037 Focus to learn more arXiv-issued DOI via DataCite

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Full text under the publisher's open licence · 269 words

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