Privacy-Preserving Generation of Clinical Narratives from Medical Terminologies

Abstract:In high-stakes domains such as healthcare, privacy concerns severely limit the use of real-world training data. Differentially private (DP) synthetic data offers a promising alternative with formal privacy guarantees, but achieving strong utility remains challenging for clinical note generation due to domain specificity and long-form text complexity. We present Term2Note, a method for synthesising full-length clinical notes under DP constraints. By structurally separating content and form, Term2Note generates section-wise note content conditioned on medical terms, with terms and notes privatised under separate DP constraints, and applies a DP quality maximiser to improve outputs. Experiments demonstrate that Term2Note produces synthetic notes with statistical properties closely aligned with real clinical notes, and that downstream models trained on these notes achieve performance comparable to those trained on real clinical data. Compared to existing DP text generation baselines, Term2Note substantially improves both fidelity and utility, without relying on label distribution assumptions, highlighting its effectiveness as a practical privacy-preserving alternative to real clinical notes.

Computation and Language (cs.CL)

arXiv:2509.10882 [cs.CL]

(or arXiv:2509.10882v2 [cs.CL] for this version)

https://doi.org/10.48550/arXiv.2509.10882 Focus to learn more arXiv-issued DOI via DataCite

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