aiqbench analysis
This research introduces PPIM, a novel neural solver that outperforms standard PINN and generic Mamba models in simulating 3D bioheat transfer equations under localized heat sources. By integrating conditioned inputs with Pennes-aware state-space model decay initialization, the method achieves superior accuracy in predicting transient temperature distributions relevant to microwave ablation scenarios. The study validates the efficacy of physics-informed architectures specifically tailored for solving complex partial differential equations in biomedical thermal modeling.
PPIM: Pennes Physics-Informed Mamba for Heat-Source-Conditioned 3D Bioheat Simulation
arXiv:2609.06869v1 Announce Type: new Abstract: Three-dimensional bioheat simulation aims to predict transient temperature distributions in biological tissue and is commonly modeled using the Pennes bioheat equation, which combines thermal diffusion, perfusion-mediated heat loss, and external heat generation. In this study, we consider a controlled 3D Pennes bioheat simulation under a localized heat-source condition inspired by microwave ablation (MWA). To evaluate neural approximation performance, we compare three neural partial differential equation (PDE) solvers under the same controlled simulation: a spatial Fourier-feature physics-informed neural network (PINN), a generic PINNMamba temporal subsequence model, and Pennes Physics-Informed Mamba (PPIM). PPIM builds on the temporal subsequence model by incorporating conditioned heat-source input and Pennes-aware state-space model (SSM) decay initialization. All three neural models are trained under the same conditions with the same Pennes residual, and an explicit finite-difference method (FDM) solution is used only as the numerical reference. In a representative 600~s run, PPIM achieved the lowest MAE, relative $L_1$ error, and relative $L_2$ error among the evaluated neural solvers. Error maps further showed that the remaining PPIM errors were more concentrated near the heat-source region than across the rest of the domain. These results indicate that PPIM is effective for approximating the FDM reference final temperature field in this controlled simulation. The source code is available at https://github.com/muvYun/PPIM.
Abstract:Three-dimensional bioheat simulation aims to predict transient temperature distributions in biological tissue and is commonly modeled using the Pennes bioheat equation, which combines thermal diffusion, perfusion-mediated heat loss, and external heat generation. In this study, we consider a controlled 3D Pennes bioheat simulation under a localized heat-source condition inspired by microwave ablation (MWA). To evaluate neural approximation performance, we compare three neural partial differential equation (PDE) solvers under the same controlled simulation: a spatial Fourier-feature physics-informed neural network (PINN), a generic PINNMamba temporal subsequence model, and Pennes Physics-Informed Mamba (PPIM). PPIM builds on the temporal subsequence model by incorporating conditioned heat-source input and Pennes-aware state-space model (SSM) decay initialization. All three neural models are trained under the same conditions with the same Pennes residual, and an explicit finite-difference method (FDM) solution is used only as the numerical reference. In a representative 600~s run, PPIM achieved the lowest MAE, relative $L_1$ error, and relative $L_2$ error among the evaluated neural solvers. Error maps further showed that the remaining PPIM errors were more concentrated near the heat-source region than across the rest of the domain. These results indicate that PPIM is effective for approximating the FDM reference final temperature field in this controlled simulation. The source code is available at this https URL.
Machine Learning (cs.LG); Mathematical Physics (math-ph)
arXiv:2609.06869 [cs.LG]
(or arXiv:2609.06869v1 [cs.LG] for this version)
https://doi.org/10.48550/arXiv.2609.06869 Focus to learn more arXiv-issued DOI via DataCite (pending registration)
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