aiqbench analysis
PathoSage addresses critical reliability issues in computational pathology by decoupling evidence collection from adjudication to prevent context contamination and hallucinations. The framework introduces a training-free experience system that models long-term tool reliability, effectively mitigating classifier disagreement in patch-level reasoning tasks. This approach establishes explicit evidence deliberation and reliability-aware modeling as essential components for building robust agentic workflows in high-stakes medical imaging.
PathoSage: Towards Multi-Source Evidence Adjudication in Pathology via Experience-Aware Agentic Workflow
arXiv:2606.07549v1 Announce Type: new Abstract: Recent advances in Multimodal Large Language Models (MLLMs) and agent workflows have shown strong promise for computational pathology, yet reliable patch-level reasoning remains challenging. End-to-end pathology MLLMs often hallucinate morphological features, while recent agentic systems usually merge tool outputs and retrieved knowledge into a shared context, making decisions vulnerable to conflicting evidence and context contamination. We propose PathoSage, a three-stage framework that explicitly separates knowledge retrieval, evidence collection, and evidence adjudication for patch-level pathology multimodal reasoning. Its core component, Structured Evidence Deliberation, independently evaluates heterogeneous evidence from tools, performs conflict analysis, and generates the final judgment in a fresh context to reduce anchoring bias. We further introduce a training-free Beta-Bernoulli experience system with continuous credit assignment to model long-term tool reliability and construct similarity-weighted priors for future tool use. Experiments show that PathoSage effectively mitigates VQA hallucinations and classifier disagreement, outperforming strong pathology MLLM and agentic baselines. Our results highlight explicit evidence adjudication and reliability-aware tool modeling as key ingredients for robust pathology agents.
Abstract:Recent advances in Multimodal Large Language Models (MLLMs) and agent workflows have shown strong promise for computational pathology, yet reliable patch-level reasoning remains challenging. End-to-end pathology MLLMs often hallucinate morphological features, while recent agentic systems usually merge tool outputs and retrieved knowledge into a shared context, making decisions vulnerable to conflicting evidence and context contamination. We propose PathoSage, a three-stage framework that explicitly separates knowledge retrieval, evidence collection, and evidence adjudication for patch-level pathology multimodal reasoning. Its core component, Structured Evidence Deliberation, independently evaluates heterogeneous evidence from tools, performs conflict analysis, and generates the final judgment in a fresh context to reduce anchoring bias. We further introduce a training-free Beta-Bernoulli experience system with continuous credit assignment to model long-term tool reliability and construct similarity-weighted priors for future tool use. Experiments show that PathoSage effectively mitigates VQA hallucinations and classifier disagreement, outperforming strong pathology MLLM and agentic baselines. Our results highlight explicit evidence adjudication and reliability-aware tool modeling as key ingredients for robust pathology agents.
Artificial Intelligence (cs.AI); Multiagent Systems (cs.MA)
arXiv:2606.07549 [cs.AI]
(or arXiv:2606.07549v1 [cs.AI] for this version)
https://doi.org/10.48550/arXiv.2606.07549 Focus to learn more arXiv-issued DOI via DataCite
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Full text under the publisher's open licence · 259 words
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