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Med-R$^3$ addresses a critical gap in medical AI by jointly optimizing retrieval and reasoning capabilities through progressive reinforcement learning, avoiding the limitations of isolated training or rigid supervised fine-tuning. The framework demonstrates significant performance gains over leading closed-source models when applied to complex medical problem-solving contexts where external knowledge integration is essential.
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Med-R$^3$: Enhancing Medical Retrieval-Augmented Reasoning of LLMs via Progressive Reinforcement Learning

arXiv3 min read

arXiv:2507.23541v5 Announce Type: replace Abstract: In medical scenarios, effectively retrieving external knowledge and leveraging it for rigorous logical reasoning is of significant importance. Despite their potential, existing work has predominantly focused on enhancing either retrieval or reasoning capabilities of the models in isolation, with little attention given to their joint optimization, which leads to limited coordination between the two processes. Additionally, current methods rely heavily on supervised fine-tuning (SFT), which can cause models to memorize existing problem-solving pathways, thereby restricting their generalization ability when confronted with novel problem contexts. Furthermore, while some studies have explored to improve retrieval-augmented reasoning in general domains via reinforcement learning, their reward function designs do not adequately capture the specific demands of the medical domain. To address these challenges, we introduce **Med-R$^3$**, a **Med**ical **R**etrieval-augmented **R**easoning framework driven by progressive **R**einforcement learning. In this framework, we first develop the model's ability to perform logical reasoning over medical problems. Subsequently, on the basis of this foundation, we adaptively optimize the retrieval capability to better align with the characteristics of knowledge corpus and external information utilization throughout the reasoning process. Finally, we conduct joint optimization of the model's retrieval and reasoning coordination. Extensive experiments indicate that **Med-R$^3$** could achieve state-of-the-art performances, with Qwen3-8B + Med-R$^3$ surpassing closed-sourced GPT-4o-mini by 12.22% at a comparable parameter scale, while Qwen2.5-14B augmented with \ours shows a more substantial gain of 16.31%.

Abstract:In medical scenarios, effectively retrieving external knowledge and leveraging it for rigorous logical reasoning is of significant importance. Despite their potential, existing work has predominantly focused on enhancing either retrieval or reasoning capabilities of the models in isolation, with little attention given to their joint optimization, which leads to limited coordination between the two processes. Additionally, current methods rely heavily on supervised fine-tuning (SFT), which can cause models to memorize existing problem-solving pathways, thereby restricting their generalization ability when confronted with novel problem contexts. Furthermore, while some studies have explored to improve retrieval-augmented reasoning in general domains via reinforcement learning, their reward function designs do not adequately capture the specific demands of the medical domain. To address these challenges, we introduce **Med-R$^3$**, a **Med**ical **R**etrieval-augmented **R**easoning framework driven by progressive **R**einforcement learning. In this framework, we first develop the model's ability to perform logical reasoning over medical problems. Subsequently, on the basis of this foundation, we adaptively optimize the retrieval capability to better align with the characteristics of knowledge corpus and external information utilization throughout the reasoning process. Finally, we conduct joint optimization of the model's retrieval and reasoning coordination. Extensive experiments indicate that **Med-R$^3$** could achieve state-of-the-art performances, with Qwen3-8B + Med-R$^3$ surpassing closed-sourced GPT-4o-mini by 12.22% at a comparable parameter scale, while Qwen2.5-14B augmented with \ours shows a more substantial gain of 16.31%.

Computation and Language (cs.CL)

arXiv:2507.23541 [cs.CL]

(or arXiv:2507.23541v5 [cs.CL] for this version)

Full text under the publisher's open licence · 237 words

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