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This research applies large-scale pretraining strategies to deep learning models for correcting geometric distortions in diffusion-weighted MRI, demonstrating superior performance over non-pretrained baselines. While the approach shows promise for resource-constrained settings, it highlights critical transferability challenges when deploying models across different acquisition environments without harmonized preprocessing. The study underscores the necessity of robust generalization techniques for medical imaging AI to function effectively beyond narrow training distributions.
Source coveringarXiv

Large-Scale Pretraining for Improving Deep Learning-Based Geometric Distortion Correction of Diffusion-Weighted Imaging

arXiv2 min read

arXiv:2609.06437v1 Announce Type: cross Abstract: Diffusion-weighted imaging (DWI) is widely used in clinical settings but remains vulnerable to geometric distortion. Conventional correction methods often require additional acquisitions or vendor-specific solutions, limiting their feasibility in high-throughput, resource-constrained settings. This study investigates whether large-scale pretraining strategies can improve deep learning-based distortion correction for single-phase-encoding DWI. We formulate the task as image reconstruction, and compare a non-pretrained baseline against a self-supervised and a generative pretrained model, evaluated using both quantitative image-similarity metrics and qualitative expert assessment. The best-performing model was further tested for transferability on data collected in an LMIC setting with acquisition shift. Pretrained models outperformed the non-pretrained baseline, with cWDM achieving the strongest results across both quantitative and qualitative evaluation. However, application to LMIC data revealed transferability challenges, including contrast alteration and over-reliance on T1-weighted anatomical structure. Registering images to a common standard space improved predictions, suggesting that harmonized preprocessing may enhance cross-domain deployment.

Abstract:Diffusion-weighted imaging (DWI) is widely used in clinical settings but remains vulnerable to geometric distortion. Conventional correction methods often require additional acquisitions or vendor-specific solutions, limiting their feasibility in high-throughput, resource-constrained settings. This study investigates whether large-scale pretraining strategies can improve deep learning-based distortion correction for single-phase-encoding DWI. We formulate the task as image reconstruction, and compare a non-pretrained baseline against a self-supervised and a generative pretrained model, evaluated using both quantitative image-similarity metrics and qualitative expert assessment. The best-performing model was further tested for transferability on data collected in an LMIC setting with acquisition shift. Pretrained models outperformed the non-pretrained baseline, with cWDM achieving the strongest results across both quantitative and qualitative evaluation. However, application to LMIC data revealed transferability challenges, including contrast alteration and over-reliance on T1-weighted anatomical structure. Registering images to a common standard space improved predictions, suggesting that harmonized preprocessing may enhance cross-domain deployment.

Computer Vision and Pattern Recognition (cs.CV); Machine Learning (cs.LG)

arXiv:2609.06437 [cs.CV]

(or arXiv:2609.06437v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2609.06437 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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