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This research advances causal inference by introducing SPICE-Net, a neural network framework capable of estimating treatment effects using only a single proxy variable for unobserved confounders. The study extends theoretical bounds to multi-dimensional continuous settings and flexible functional relationships, offering a robust tool for scenarios where traditional randomized trials are infeasible. By leveraging known error mechanisms between proxies and confounders, the method effectively mitigates bias without requiring full observability of hidden variables.
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Identifying Causal Effects Using a Single Proxy Variable

arXiv2 min read

arXiv:2604.09135v2 Announce Type: replace-cross Abstract: Unobserved confounding is a key challenge when estimating causal effects from a treatment on an outcome. In this work, we assume that we observe a single, potentially multi-dimensional proxy variable of the unobserved confounder and that we know the mechanism that generates the proxy from the confounder. Under an assumption called Single Proxy Identifiability of Causal Effects or simply SPICE, we prove that this error mechanism is complete and causal effects are identifiable. We extend the proxy-based causal identifiability results by Kuroki and Pearl (2014); Pearl (2010) to multi-dimensional continuous settings, more flexible functional relationships and a broader class of distributions. Further, we develop a neural network based estimation framework, SPICE-Net, to estimate causal effects, which is applicable to both discrete and continuous treatments.

Abstract:Unobserved confounding is a key challenge when estimating causal effects from a treatment on an outcome. In this work, we assume that we observe a single, potentially multi-dimensional proxy variable of the unobserved confounder and that we know the mechanism that generates the proxy from the confounder. Under an assumption called Single Proxy Identifiability of Causal Effects or simply SPICE, we prove that this error mechanism is complete and causal effects are identifiable. We extend the proxy-based causal identifiability results by Kuroki and Pearl (2014); Pearl (2010) to multi-dimensional continuous settings, more flexible functional relationships and a broader class of distributions. Further, we develop a neural network based estimation framework, SPICE-Net, to estimate causal effects, which is applicable to both discrete and continuous treatments.

Machine Learning (stat.ML); Machine Learning (cs.LG); Statistics Theory (math.ST); Methodology (stat.ME)

arXiv:2604.09135 [stat.ML]

(or arXiv:2604.09135v2 [stat.ML] for this version)

https://doi.org/10.48550/arXiv.2604.09135 Focus to learn more arXiv-issued DOI via DataCite

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Full text under the publisher's open licence · 224 words

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