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This study presents a novel multimodal framework that integrates eye-tracking data to improve the spatial grounding and diagnostic accuracy of chest X-ray analysis models. By fusing radiologist fixations with image patches and transcription embeddings, the approach significantly boosts AUC and F1 scores while enhancing the transparency of generated medical reports. The work establishes a reproducible benchmark for interpretable vision-language models in clinical settings, addressing key limitations in current medical AI regarding attention alignment.
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Eyes on the Image: Gaze Supervised Multimodal Learning for Chest X-ray Diagnosis and Report Generation

arXiv2 min read

arXiv:2508.13068v2 Announce Type: replace-cross Abstract: Medical vision-language models still struggle to match radiologists' attention and to verbalize findings with explicit spatial grounding. We address this gap with a two-stage multimodal framework for chest X-ray interpretation built on the MIMIC-Eye dataset. In the first stage introduces a gaze-token classifier that fuses image patches, bounding-box masks, transcription embeddings, and radiologist fixations. A curriculum-scheduled, trust-calibrated composite loss supervises the gaze token, boosting both accuracy and spatial alignment. Adding fixation supervision raises AUC 4.4% and F1 13.3%, and Pearson correlation rises to 0.306, confirming clinically relevant focus. In stage 2, classifier predictions are translated into region-specific diagnostic sentences. Confidence-weighted keywords are extracted, mapped to 17 thoracic regions through an expert dictionary, and expanded with a prompted large language model, boosting clinical-term BERTScore and ROUGE scores over keyword baselines. All components are toggle-able for ablation, and the full pipeline is reproducible, offering a new benchmark for interpretable, gaze-aware chest-X-ray analysis. Integrating eye-tracking signals demonstrably enhances both diagnostic accuracy and the transparency of generated reports.

Abstract:Medical vision-language models still struggle to match radiologists' attention and to verbalize findings with explicit spatial grounding. We address this gap with a two-stage multimodal framework for chest X-ray interpretation built on the MIMIC-Eye dataset. In the first stage introduces a gaze-token classifier that fuses image patches, bounding-box masks, transcription embeddings, and radiologist fixations. A curriculum-scheduled, trust-calibrated composite loss supervises the gaze token, boosting both accuracy and spatial alignment. Adding fixation supervision raises AUC 4.4% and F1 13.3%, and Pearson correlation rises to 0.306, confirming clinically relevant focus. In stage 2, classifier predictions are translated into region-specific diagnostic sentences. Confidence-weighted keywords are extracted, mapped to 17 thoracic regions through an expert dictionary, and expanded with a prompted large language model, boosting clinical-term BERTScore and ROUGE scores over keyword baselines. All components are toggle-able for ablation, and the full pipeline is reproducible, offering a new benchmark for interpretable, gaze-aware chest-X-ray analysis. Integrating eye-tracking signals demonstrably enhances both diagnostic accuracy and the transparency of generated reports.

Computer Vision and Pattern Recognition (cs.CV); Machine Learning (cs.LG)

arXiv:2508.13068 [cs.CV]

(or arXiv:2508.13068v2 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2508.13068 Focus to learn more arXiv-issued DOI via DataCite

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Full text under the publisher's open licence · 262 words

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