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DisMix addresses a critical gap in medical imaging by adapting data augmentation techniques specifically for ordinal classification tasks, where standard methods fail to preserve disease severity hierarchies. By disentangling appearance features from rank-based signals using a dual-codebook VQ-VAE, the framework maintains structural integrity while enhancing model robustness across diverse clinical datasets. This approach represents significant progress in applying advanced machine learning architectures to solve nuanced problems in healthcare diagnostics without relying on general-purpose AI hype.
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DisMix: Order-Aware Mixup for Medical Imaging via Disentangling Ordinal and Non-Ordinal Features

arXiv2 min read

arXiv:2608.04652v1 Announce Type: cross Abstract: Image mixup is a widely adopted data augmentation strategy, yet it is ill-suited for ordinal classification tasks such as medical disease grading, where labels encode a progression of severity. By indiscriminately blending disease-severity cues (ordinal) with appearance-level variation (non-ordinal), standard mixup produces samples that distort the very ordinal structure that underpins clinical severity grading. We introduce DisMix, an order-aware mixup framework for ordinal classification. DisMix disentangles ordinal and non-ordinal features via a dual-codebook VQ-VAE, allowing each subspace to be mixed independently: ordinal codes are interpolated to produce meaningful intermediate ranks, while non-ordinal codes are varied to introduce appearance diversity without corrupting the ordinal signal. Across four medical imaging datasets, DisMix shows the best aggregate performance among six image mixup baselines paired with six ordinal classifiers and remains effective under data scarcity and clinical grading variability.

Abstract:Image mixup is a widely adopted data augmentation strategy, yet it is ill-suited for ordinal classification tasks such as medical disease grading, where labels encode a progression of severity. By indiscriminately blending disease-severity cues (ordinal) with appearance-level variation (non-ordinal), standard mixup produces samples that distort the very ordinal structure that underpins clinical severity grading. We introduce DisMix, an order-aware mixup framework for ordinal classification. DisMix disentangles ordinal and non-ordinal features via a dual-codebook VQ-VAE, allowing each subspace to be mixed independently: ordinal codes are interpolated to produce meaningful intermediate ranks, while non-ordinal codes are varied to introduce appearance diversity without corrupting the ordinal signal. Across four medical imaging datasets, DisMix shows the best aggregate performance among six image mixup baselines paired with six ordinal classifiers and remains effective under data scarcity and clinical grading variability.

Computer Vision and Pattern Recognition (cs.CV); Artificial Intelligence (cs.AI)

arXiv:2608.04652 [cs.CV]

(or arXiv:2608.04652v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2608.04652 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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Full text under the publisher's open licence · 235 words

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