aiqbench analysis
This research investigates the internal representational shifts of Vision Foundation Models adapted via LoRA for medical imaging, revealing that models with similar segmentation performance exhibit divergent cross-task transfer dynamics. The study identifies that early-to-mid layers are causally sufficient for task recovery, offering a parameter-efficient adaptation strategy that mitigates negative interference in secondary tasks like disease classification.
Convergent Performance, Divergent Mechanisms in LoRA-Adapted Vision Foundation Models for Brain MRI
arXiv:2610.28255v1 Announce Type: cross Abstract: Adapting Vision Foundation Models (VFMs) to medical imaging via LoRA has become standard practice, yet model selection is guided almost entirely by downstream task metrics, treating backbones with similar performance as interchangeable. We investigate whether equal performance implies equal internal representational shift. We analyse four ViT-B/16 backbones, DINOv3, SigLIP2, MerMED-FM, and BiomedCLIP, pre-trained with different objectives (self-distillation vs. contrastive vision-language) and on different data domains (natural vs. medical images). We adapt each to brain tumour segmentation and evaluate on six datasets covering both segmentation and Alzheimer's disease classification. Using attention divergence, weight-change analysis, and activation patching, we find that the four models converge to similar segmentation performance (mean Dice 78-81%) through markedly different internal dynamics, yet diverge in cross-task transfer: segmentation adaptation improves Alzheimer's disease classification for DINOv3 but degrades it for the other three backbones. We reveal a dissociation between modification magnitude and causal importance: the most heavily modified layers are not the causally relevant ones, with early-to-mid layers identified as sufficient for segmentation recovery. Restricting LoRA to these layers matches or approaches full-layer segmentation while reducing classification degradation in the three affected backbones, providing a mechanistically grounded strategy that is more parameter-efficient and more robust than standard full-layer adaptation.
Abstract:Adapting Vision Foundation Models (VFMs) to medical imaging via LoRA has become standard practice, yet model selection is guided almost entirely by downstream task metrics, treating backbones with similar performance as interchangeable. We investigate whether equal performance implies equal internal representational shift. We analyse four ViT-B/16 backbones, DINOv3, SigLIP2, MerMED-FM, and BiomedCLIP, pre-trained with different objectives (self-distillation vs. contrastive vision-language) and on different data domains (natural vs. medical images). We adapt each to brain tumour segmentation and evaluate on six datasets covering both segmentation and Alzheimer's disease classification. Using attention divergence, weight-change analysis, and activation patching, we find that the four models converge to similar segmentation performance (mean Dice 78-81%) through markedly different internal dynamics, yet diverge in cross-task transfer: segmentation adaptation improves Alzheimer's disease classification for DINOv3 but degrades it for the other three backbones. We reveal a dissociation between modification magnitude and causal importance: the most heavily modified layers are not the causally relevant ones, with early-to-mid layers identified as sufficient for segmentation recovery. Restricting LoRA to these layers matches or approaches full-layer segmentation while reducing classification degradation in the three affected backbones, providing a mechanistically grounded strategy that is more parameter-efficient and more robust than standard full-layer adaptation.
Computer Vision and Pattern Recognition (cs.CV); Machine Learning (cs.LG)
arXiv:2610.28255 [cs.CV]
(or arXiv:2610.28255v1 [cs.CV] for this version)
https://doi.org/10.48550/arXiv.2610.28255 Focus to learn more arXiv-issued DOI via DataCite (pending registration)
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website.
Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them.
Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Full text under the publisher's open licence · 301 words