aiqbench analysis
This paper addresses a critical bottleneck in clinical AI by introducing a continual meta-learning framework that prevents catastrophic forgetting when integrating new, unlabeled patient data sequentially. By combining set-conditioned surrogates with a Bayesian Gaussian Mixture Model, the method enables dynamic identification of data sources while maintaining computational scalability. This approach offers a practical pathway for deploying personalized neural surrogates in real-world settings where full model retraining is operationally infeasible.
CoMetaPNS: Continually Meta-learning Personalized Neural Surrogates for Cardiac Electrophysiology Simulations
arXiv:2606.07488v1 Announce Type: new Abstract: Personalized virtual heart simulations face challenges in model personalization and computational cost. While neural surrogates offer state-of-the-art solutions, they typically address either efficient personalization or training generalizable models. Recent work reframes this by learning the process of personalizing a surrogate using limited subject-specific context data, through few-shot generative modeling with set-conditioned surrogates and meta-learned amortized inference. These methods, however, assume a static and diverse training distribution with known task identifiers. When new data becomes available, they require costly retraining with all prior data to avoid catastrophic forgetting - a phenomena where the model forgets earlier tasks when trained on new ones. This is a major limitation in clinical settings where often unlabeled data arrives sequentially and full retraining is infeasible. This paper presents a new continual meta-learning framework to achieve personalized neural surrogates able to not only continually integrate information but also identify whether incoming data stems from a known or unknown dynamics source. By leveraging a continual Bayesian Gaussian Mixture Model over a memory buffer, our framework can infer the identifiers and relationships of data over time - required for effective meta-learning. Empirical results on synthetic cardiac data demonstrate superior simulation forecasting, computational scalability, and resilience to catastrophic forgetting compared to existing baselines.
Abstract:Personalized virtual heart simulations face challenges in model personalization and computational cost. While neural surrogates offer state-of-the-art solutions, they typically address either efficient personalization or training generalizable models. Recent work reframes this by learning the process of personalizing a surrogate using limited subject-specific context data, through few-shot generative modeling with set-conditioned surrogates and meta-learned amortized inference. These methods, however, assume a static and diverse training distribution with known task identifiers. When new data becomes available, they require costly retraining with all prior data to avoid catastrophic forgetting - a phenomena where the model forgets earlier tasks when trained on new ones. This is a major limitation in clinical settings where often unlabeled data arrives sequentially and full retraining is infeasible. This paper presents a new continual meta-learning framework to achieve personalized neural surrogates able to not only continually integrate information but also identify whether incoming data stems from a known or unknown dynamics source. By leveraging a continual Bayesian Gaussian Mixture Model over a memory buffer, our framework can infer the identifiers and relationships of data over time - required for effective meta-learning. Empirical results on synthetic cardiac data demonstrate superior simulation forecasting, computational scalability, and resilience to catastrophic forgetting compared to existing baselines.
Machine Learning (cs.LG)
arXiv:2606.07488 [cs.LG]
(or arXiv:2606.07488v1 [cs.LG] for this version)
https://doi.org/10.48550/arXiv.2606.07488 Focus to learn more arXiv-issued DOI via DataCite (pending registration)
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