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This study introduces MedQADE, a new German-language benchmark revealing that while frontier LLMs can statistically align with physician scoring on medical tasks, they lack the clinical caution to abstain from judging difficult cases where humans would hesitate. The research highlights critical risks of lineage-dependent bias and insufficient metacognition in automated evaluators, indicating that statistical agreement does not equate to safe or calibrated clinical judgment. These findings underscore the necessity for explicit verification protocols before deploying LLM-as-Judge systems in high-stakes medical environments.
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Clinician-Level Agreement Without Clinical Caution: LLM Evaluator Limits in Medical AI Benchmarking

arXiv2 min read

arXiv:2607.01103v2 Announce Type: replace Abstract: Open-response evaluation provides stronger clinical validity than multiple-choice benchmarks but creates a scoring bottleneck that motivates automated LLM-asa-Judge approaches. Whether such evaluators replicate clinical calibration and caution, however, remains untested. We introduce MedQADE, the first standardised open-response clinical benchmark for German, a major clinical language lacking native evaluation infrastructure, comprising 3,800 items annotated by ten practising physicians and nine Large Language Model (LLM) evaluators. The top-performing evaluator model, Gemini 3 Flash, reached alignment consistent with the physician ceiling (\k{appa} = 0.694 vs. \k{appa} = 0.709), though wide confidence intervals limit interpretation. Despite this statistical alignment, automated evaluators exhibited near-absent clinical metacognition: physicians scaled abstention with item difficulty, while frontier models assigned definitive scores in every case. We additionally quantified systematic lineage-dependent biases, where models preferentially scored architectural siblings, an effect independent of language. These results show that statistical alignment does not ensure clinical caution, and that evaluator independence requires explicit verification.

Authors:William Philipp, Finn Fassbender, Daniel Fister, Thorsten Langer, Martje G. Pauly, Rebecca Herzog, Markus A. Hobert, Theresa Paulus, Alexander Baumann, Chi Wang Ip, Lukas L. Goede, Johanna Reimer, Sebastian Löns, Ronald Böck, Sebastian Fudickar

Abstract:Open-response evaluation provides stronger clinical validity than multiple-choice benchmarks but creates a scoring bottleneck that motivates automated LLM-asa-Judge approaches. Whether such evaluators replicate clinical calibration and caution, however, remains untested. We introduce MedQADE, the first standardised open-response clinical benchmark for German, a major clinical language lacking native evaluation infrastructure, comprising 3,800 items annotated by ten practising physicians and nine Large Language Model (LLM) evaluators. The top-performing evaluator model, Gemini 3 Flash, reached alignment consistent with the physician ceiling (\k{appa} = 0.694 vs. \k{appa} = 0.709), though wide confidence intervals limit interpretation. Despite this statistical alignment, automated evaluators exhibited near-absent clinical metacognition: physicians scaled abstention with item difficulty, while frontier models assigned definitive scores in every case. We additionally quantified systematic lineage-dependent biases, where models preferentially scored architectural siblings, an effect independent of language. These results show that statistical alignment does not ensure clinical caution, and that evaluator independence requires explicit verification.

Computation and Language (cs.CL)

arXiv:2607.01103 [cs.CL]

(or arXiv:2607.01103v2 [cs.CL] for this version)

Full text under the publisher's open licence · 197 words

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