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This research applies graph neural networks to model cardiac electrophysiology, demonstrating high precision in detecting arrhythmia targets from sparse intracardiac measurements. The study highlights the potential of GNNs for generalizing across complex 2D curved surfaces with minimal fine-tuning, offering a promising pathway toward clinical deployment in PVC ablation procedures.
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Characterising cardiac tissue properties with graph neural networks

arXiv2 min read

arXiv:2608.15843v1 Announce Type: cross Abstract: Characterising electrophysiological properties of cardiac tissue efficiently and accurately from spatially sparse intracardiac measurements is clinically important for localising ablation targets and improving arrhythmia treatment. We developed a graph neural network-based framework trained on synthetic electrogram signals on 2D flat surfaces to identify areas of interest in the context of cardiac ablation for premature ventricular complexes (PVCs). Our method achieved an average precision of 0.96, 0.97, and 0.95 for the detection of single-patch fibrosis, rapid depolarisation and high excitability, respectively. The trained model can then be applied to 2D curved surfaces with few-shot fine-tuning, demonstrating its generalisation capability. Future work will develop this framework further for clinical use in PVC ablation.

Abstract:Characterising electrophysiological properties of cardiac tissue efficiently and accurately from spatially sparse intracardiac measurements is clinically important for localising ablation targets and improving arrhythmia treatment. We developed a graph neural network-based framework trained on synthetic electrogram signals on 2D flat surfaces to identify areas of interest in the context of cardiac ablation for premature ventricular complexes (PVCs). Our method achieved an average precision of 0.96, 0.97, and 0.95 for the detection of single-patch fibrosis, rapid depolarisation and high excitability, respectively. The trained model can then be applied to 2D curved surfaces with few-shot fine-tuning, demonstrating its generalisation capability. Future work will develop this framework further for clinical use in PVC ablation.

Quantitative Methods (q-bio.QM); Artificial Intelligence (cs.AI); Signal Processing (eess.SP)

arXiv:2608.15843 [q-bio.QM]

(or arXiv:2608.15843v1 [q-bio.QM] for this version)

https://doi.org/10.48550/arXiv.2608.15843 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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Full text under the publisher's open licence · 211 words

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