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This research demonstrates a viable architecture for using agentic AI and RAG to create high-fidelity VR simulations for training in complex medical procedures like HDR brachytherapy. By grounding interactions in clinical guidelines via LLMs, the system enables safe, hands-free guidance that overcomes physical safety constraints associated with radioactive sources. The prototype's successful deployment on consumer-grade hardware suggests a scalable path for integrating advanced AI agents into specialized medical education frameworks.
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Agentic AI-driven Immersive Simulation: A Knowledge-Aware Virtual Training Platform for High Dose Rate (HDR) Brachytherapy

arXiv2 min read

arXiv:2608.08163v2 Announce Type: replace Abstract: The convergence of the Metaverse and Large Language Model (LLM)-based AI agent is catalyzing a shift toward autonomous, immersive, and personalized pedagogical frameworks in medical education. This paper presents a novel agentic AI-driven immersive simulation specifically designed for High Dose Rate (HDR) vaginal cylinder (VC) brachytherapy in cancer care. By integrating Virtual Reality (VR) and mobile computing, the system establishes a high-fidelity, risk-free environment that allows trainees to master complex procedural skills without the facility or safety constraints posed by physical anatomy or live radioactive sources. A core contribution of this work is the seamless integration of a knowledge-aware assistant leveraging Retrieval-Augmented Generation (RAG) to ground agent interactions in authoritative clinical guidelines. This architecture also enables an interactive agent to provide natural language interfaces and hands-free, real-time guidance during intricate medical maneuvers. We validate the proposed system through a prototype deployment comprising a Meta Quest 3 interface linked to a local GPU-accelerated AI backend, demonstrating a feasible architecture for HDR brachytherapy simulation. Experimental results indicate that the system maintains suitable end-to-end latency and high context precision, answer completeness, and relevance in the RAG-enhanced pedagogical support.

Abstract:The convergence of the Metaverse and Large Language Model (LLM)-based AI agent is catalyzing a shift toward autonomous, immersive, and personalized pedagogical frameworks in medical education. This paper presents a novel agentic AI-driven immersive simulation specifically designed for High Dose Rate (HDR) vaginal cylinder (VC) brachytherapy in cancer care. By integrating Virtual Reality (VR) and mobile computing, the system establishes a high-fidelity, risk-free environment that allows trainees to master complex procedural skills without the facility or safety constraints posed by physical anatomy or live radioactive sources. A core contribution of this work is the seamless integration of a knowledge-aware assistant leveraging Retrieval-Augmented Generation (RAG) to ground agent interactions in authoritative clinical guidelines. This architecture also enables an interactive agent to provide natural language interfaces and hands-free, real-time guidance during intricate medical maneuvers. We validate the proposed system through a prototype deployment comprising a Meta Quest 3 interface linked to a local GPU-accelerated AI backend, demonstrating a feasible architecture for HDR brachytherapy simulation. Experimental results indicate that the system maintains suitable end-to-end latency and high context precision, answer completeness, and relevance in the RAG-enhanced pedagogical support.

Artificial Intelligence (cs.AI)

arXiv:2608.08163 [cs.AI]

(or arXiv:2608.08163v2 [cs.AI] for this version)

https://doi.org/10.48550/arXiv.2608.08163 Focus to learn more arXiv-issued DOI via DataCite

https://doi.org/10.1109/CHASE69719.2026.00069 Focus to learn more DOI(s) linking to related resources

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Full text under the publisher's open licence · 287 words

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