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This arXiv preprint proposes hierarchical models that predict at low resolution, certify the signal with conformal risk control, and refine only the certified regions. The authors report 2.5 to 72x wall-clock speedups on 3D medical segmentation, galaxy flux prediction, and calcium spike rate prediction, including on CPUs. For ML practitioners working with large scientific data, the key point is that the method pairs efficiency gains with formal risk guarantees, though the reported speedups are the authors' own benchmarks and need independent replication.
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Adaptive Computation with Conformal Certification

arXiv2 min read

arXiv:2610.19189v1 Announce Type: new Abstract: Scientific imaging data involving medical (e.g., 3D radiographic, microscopic images) and astronomical sensors pose different challenges from natural images. One key challenge is that these datasets are often orders of magnitude larger than natural images. Efficient training and inference on such data is challenging due to the increased hardware requirements, often needing bespoke solutions. Moreover, the relevant objects such as tumors and astronomical phenomena are sparsely distributed with respect to the background information. Standard efficiency techniques like quantization and pruning apply uniform scaling of all regions, potentially compromising the precision/fidelity of predictions. Thus, efficient methods that reduce computational requirements without losing resolution for relevant parts of the data and with uncertainty estimates on predictions are essential. We present \textit{Conformal Adaptation} with risk guarantees for uncertainty-aware sparse computations. Our formalism is general, spanning dense pixel-level classification and regression tasks where hierarchical models predict at low resolution, certify the signal using conformal risk control, and refine the certified predictions. We benchmark our method on multiple tasks such as 3D medical image segmentation, 2D galaxy flux prediction, and 1D calcium spike rate prediction, achieving $2.5$--$72\times$ wall-clock speedup across the various tasks, including on commodity CPUs.

Abstract:Scientific imaging data involving medical (e.g., 3D radiographic, microscopic images) and astronomical sensors pose different challenges from natural images. One key challenge is that these datasets are often orders of magnitude larger than natural images. Efficient training and inference on such data is challenging due to the increased hardware requirements, often needing bespoke solutions. Moreover, the relevant objects such as tumors and astronomical phenomena are sparsely distributed with respect to the background information. Standard efficiency techniques like quantization and pruning apply uniform scaling of all regions, potentially compromising the precision/fidelity of predictions. Thus, efficient methods that reduce computational requirements without losing resolution for relevant parts of the data and with uncertainty estimates on predictions are essential. We present \textit{Conformal Adaptation} with risk guarantees for uncertainty-aware sparse computations. Our formalism is general, spanning dense pixel-level classification and regression tasks where hierarchical models predict at low resolution, certify the signal using conformal risk control, and refine the certified predictions. We benchmark our method on multiple tasks such as 3D medical image segmentation, 2D galaxy flux prediction, and 1D calcium spike rate prediction, achieving $2.5$--$72\times$ wall-clock speedup across the various tasks, including on commodity CPUs.

Machine Learning (cs.LG)

arXiv:2610.19189 [cs.LG]

(or arXiv:2610.19189v1 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2610.19189 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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Full text under the publisher's open licence · 286 words

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