Skill-uri pentru agenți pe care le poți verifica înainte să le instalezi
Skill-uri SKILL.md publice din depozite GitHub cu peste 50 de stele și de la producători, scanate și evaluate. Instalează oricare dintre ele cu o singură comandă în Claude Code, Cursor, Codex, GitHub Copilot sau Gemini CLI.
36.321 de skill-uri din 1.649 de depozite · actualizat acum 2 minute
35.761 de skill-uri
- solublempnnaipoch/open-scienceInverse-fold a backbone with SolubleMPNN — ProteinMPNN retrained on a soluble-PDB subset (Dauparas et al. 2022) — for sequences biased toward cytosolic expression and reduced aggregation. Reach for this skill when designs from vanilla ProteinMPNN are aggregating or going to inclusion bodies, when redesigning a membrane-adjacent fold for soluble expression, or when an E. coli expression screen is the next step.AlteleFără avertismente★ 5,4 K↓ —
- remote-compute-sshaipoch/open-scienceEvaluate and use SSH Remote Compute before choosing where to run GPU, high-memory, parallel, batch, model-inference, bioinformatics, or other long-running scientific work; supports short remote commands and asynchronous jobs with automatic harvest and analysis.ȘtiințăFără avertismente★ 5,4 K↓ —
- alphafold2aipoch/open-sciencePredict protein structure for monomers and multimers with AlphaFold2 via the ColabFold runner (Mirdita et al. 2022, github.com/sokrypton/ColabFold; AlphaFold2 Jumper et al. 2021). Reach for this skill to fold a sequence or complex with the AF2/AF2-Multimer evoformer, to validate designed sequences by self-consistency pLDDT, ipTM, and RMSD, or to run a quick MSA-backed prediction using the public MMseqs2 server.ȘtiințăFără avertismente★ 5,4 K↓ —
- ligandmpnnaipoch/open-scienceInverse-fold a backbone with ligand, nucleic-acid, and metal context using LigandMPNN (Dauparas et al. 2023, github.com/dauparas/LigandMPNN). Reach for this skill to redesign the residues lining a binding pocket around a bound small molecule or cofactor, to design metal-coordinating sites where the geometry must be respected, or to get threaded designed-sequence PDBs out of any MPNN run.DesignFără avertismente★ 5,4 K↓ —
- customizeaipoch/open-scienceUse when the user wants to create or manage a Specialist agent or create, revise, publish, or delete a Skill through the conversational `/Customize` entry. Routes Skill work to the internal skill-creator and handles Specialist work through the JavaScript host.agents SDK.PlanificareFără avertismente★ 5,4 K↓ —
- fair-esm2aipoch/open-scienceEmbed proteins with Meta AI's ESM-2 (`fair-esm` package). Use this skill when: (1) Extracting per-residue or per-sequence embeddings for downstream ML, (2) Masked-LM likelihood / mutation effect scoring, (3) Contact prediction from a sequence.AlteleFără avertismente★ 5,4 K↓ —
- proteinmpnnaipoch/open-scienceInverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding.DesignFără avertismente★ 5,4 K↓ —
- openfold3aipoch/open-scienceStructure prediction using OpenFold3, an open-weights PyTorch reproduction of AlphaFold3 from the AlQuraishi Lab. Use this skill when predicting protein/nucleic-acid/ligand complex structures with an Apache-2.0-licensed AF3 reimplementation.ȘtiințăFără avertismente★ 5,4 K↓ —
- web3-auditelementalsouls/Claude-BugHunterSmart contract security audit — 10 DeFi bug classes (accounting desync, access control, incomplete path, off-by-one, oracle, ERC4626, reentrancy, flash loan, signature replay, proxy), pre-dive kill signals (TVL < $500K etc), Foundry PoC template, grep patterns for each class, and real Immunefi paid examples. Use for any Solidity/Rust contract audit or when deciding whether a DeFi target is worth hunting.SecuritateFără avertismente★ 5,3 K↓ —
- scgptaipoch/open-scienceEmbed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. Use this skill when: (1) Producing cell embeddings from an AnnData for clustering/integration, (2) Zero-shot or fine-tuned cell-type annotation, (3) Gene-level representation for perturbation/GRN tasks. For probabilistic single-cell models (scVI etc.), use the scvi-tools library.ȘtiințăFără avertismente★ 5,4 K↓ —
- borzoiaipoch/open-sciencePredict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. Use this skill when: (1) Scoring the regulatory effect of a variant on expression/accessibility, (2) Generating predicted coverage tracks for a locus, (3) Prioritising non-coding variants by predicted track delta.ȘtiințăFără avertismente★ 5,4 K↓ —
- diffdockaipoch/open-sciencePredict small-molecule binding poses with DiffDock-L (Corso et al. 2023/2024, github.com/gcorso/DiffDock) — blind diffusion docking that places a ligand into a protein pocket without a predefined search box and ranks the samples with a learned confidence model. Reach for this skill to dock a SMILES or SDF against a PDB, to generate ranked 3D poses for a small fragment library, or to get a starting pose for downstream rescoring. DiffDock predicts geometry, not affinity.ȘtiințăFără avertismente★ 5,4 K↓ —
- backlink-checkRyze-AI-Adgent/open-seo-mcp-skillsBacklink profile for any domain — referring domains, authority, anchors, new/lost links, and a side-by-side vs a competitor. Use when asked "check my backlinks", "backlink profile of X", "who links to them", or "link gap vs competitor".AlteleFără avertismente★ 7 K↓ —
- chai1aipoch/open-scienceStructure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai Discovery 2024, github.com/chaidiscovery/chai-lab). Reach for this skill to predict an antibody-antigen or protein-ligand complex from a single FASTA, to re-fold designed binders as an AlphaFold-multimer alternative, or to drive co-folding from Python for batched campaigns on a GPU.ȘtiințăFără avertismente★ 5,4 K↓ —
- hunt-aspnetelementalsouls/Claude-BugHunterHunt ASP.NET-specific surface — ViewState deserialization (signed-only vs encrypted), machineKey recovery, dual-parser MAC-bypass anti-pattern, request-validator bypass, trace.axd/elmah.axd disclosure, load-balanced ViewState cross-node failures, SafeControl enumeration via reflection, customErrors mode=Off stack-trace leaks, classic Webforms .aspx/.asmx/.svc surface. Built for ASP.NET Webforms + WCF + SharePoint farms.PlanificareFără avertismente★ 5,3 K↓ —
- esmfold2aipoch/open-scienceBiohub ESMFold2 / ESMFold2-Fast all-atom co-folding (Candido et al. 2026, github.com/Biohub/esm). Single-sequence and MSA modes; protein, DNA, RNA, ligand (CCD/SMILES), modified residues. FoldBench Ab-Ag 50-55%, PPI 70-77% DockQ-pass. Also covers the ESMC-{300M,600M,6B} protein language models from the same release: masked-LM logits, hidden states, mutation scoring, contact prediction, and the SAE interpretability head. MIT-licensed weights on HuggingFace org `biohub`. Use this skill when: (1) Predicting complex structures with single-sequence input, (2) Validating designed binders with ESMFold2-Fast, (3) Running ESMFold2 with MSA input, (4) Getting ESMC embeddings or per-residue mutation scores, (5) Choosing kernel backend and sampling-step settings for paper-faithful throughput.ȘtiințăFără avertismente★ 5,4 K↓ —
- boltzaipoch/open-scienceStructure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or CCD ligand, or to get an open-source AlphaFold3 alternative with optional binding-affinity prediction.ȘtiințăFără avertismente★ 5,4 K↓ —
- hunt-nodejselementalsouls/Claude-BugHunterHunt Node.js specific vulnerabilities — Prototype Pollution → RCE chains (lodash/merge/assign), Express trust proxy misconfiguration, child_process/eval injection, template engine SSTI (EJS/Pug/Handlebars), path traversal in file servers, require() injection, environment variable exfil via /proc/self/environ. Use when target runs Node.js/Express/Fastify/NestJS/Koa.SecuritateFără avertismente★ 5,3 K↓ —
- template-validationdotnet/skillsValidates custom dotnet new templates for correctness before publishing. Catches missing fields, parameter bugs, shortName conflicts, constraint issues, and common authoring mistakes that cause templates to fail silently. USE FOR: checking template.json files for errors before publishing or testing, diagnosing why a template doesn't appear after installation, reviewing template parameter definitions for type mismatches and missing defaults, finding shortName conflicts with dotnet CLI commands, validating post-action and constraint configuration. DO NOT USE FOR: finding or using existing templates (use template-discovery), creating projects from templates (use template-instantiation), creating templates from existing projects (use template-authoring).TestareFără avertismente★ 5,7 K↓ —
- mirrord-db-branchingmetalbear-co/mirrordHelps users configure mirrord.json for database branching, enabling isolated database copies for safe development and testing. Use when the user wants to set up MySQL, MariaDB, PostgreSQL, MSSQL, MongoDB, Redis, DynamoDB, ClickHouse, Google Spanner, Amazon S3, turbopuffer, or generic branches, configure copy modes, connection sources, schema migrations, IAM authentication, or manage database branches.TestareFără avertismente★ 5,4 K↓ —
- template-comparisondotnet/skillsCompares two or more dotnet new templates side by side to help users choose between them based on parameters, feature support, frameworks, and classifications. USE FOR: deciding between similar templates (webapi vs webapp, blazor vs blazorwasm, console vs worker), producing a side-by-side comparison of parameters and feature support, understanding how templates differ before creating a project. DO NOT USE FOR: creating a project from a template (use template-instantiation), authoring or validating custom templates (use template-authoring and template-validation), general single-template discovery (use template-discovery).AlteleFără avertismente★ 5,7 K↓ —
- mirrord-header-propagationmetalbear-co/mirrordMakes a codebase propagate W3C baggage (the `baggage` header carrying `mirrord-session=<key>`) end to end, so mirrord HTTP filters, preview environments, and queue splitting can route a whole request chain to one developer's session. Detects existing OpenTelemetry, Datadog, or other tracing that can already propagate baggage and enables it; otherwise adds a small propagation layer. Covers inbound/outbound HTTP and gRPC, publishing to and consuming from Kafka, RabbitMQ, SQS/SNS, GCP Pub/Sub, Azure Service Bus, NATS, Redis Pub/Sub, BullMQ and Temporal, per-message context restore in consumers, and storage hand-offs such as a GCS signed URL upload that triggers Pub/Sub or an S3 presigned upload that triggers SQS. Ends with a report of every flow found and which ones still drop the header. Use when the user asks to propagate headers, baggage, tracestate, the mirrord session key, or trace context across services or queues, or when a mirrord filter matches the first service but not downstream services or queue consDevOpsFără avertismente★ 5,4 K↓ —
- template-discoverydotnet/skillsHelps find, inspect, and compare (at a high level) .NET project templates. Resolves natural-language project descriptions to ranked template matches with pre-filled parameters. USE FOR: finding the right dotnet new template for a task, inspecting a template's parameters and constraints, understanding what a template produces before creating a project, resolving intent like "web API with auth" to concrete template + parameters. DO NOT USE FOR: actually creating projects (use template-instantiation), authoring custom templates (use template-authoring), producing a detailed side-by-side comparison (use template-comparison), choosing cross-parameter defaults during creation (use template-smart-defaults), MSBuild or build issues (use dotnet-msbuild plugin), NuGet package management unrelated to template packages.InginerieFără avertismente★ 5,7 K↓ —
- mirrord-propagation-discoverymetalbear-co/mirrordScans a live Kubernetes environment with `mirrord dump` to find an identifier mirrord can filter traffic on: a header, a `baggage` or `tracestate` member, a tenant or user id, a trace id (W3C, B3, X-Ray, Google, Jaeger), a JWT claim, a cookie, a path segment, or a JSON body field that is present on every hop of a request chain, unique to one developer's traffic, and settable by that developer. Runs mirror-only dumps on each service, sends a tagged probe request at the edge or observes real traffic, scores the candidates, and produces the matching `http_filter` (regex, jq on headers, path, method, body, or combinations) plus a per-hop report of where each identifier is dropped. Installs the mirrord CLI through a package manager when it is missing. Use when the user asks what to filter on, whether the cluster already propagates a request id or trace context, how to isolate their own requests on a shared staging cluster, how to filter on a JWT or cookie with mirrord, or wants to inspect live traffic with mirrordDevOpsFără avertismente★ 5,4 K↓ —
scgpt
aipoch/open-science
De la autor
Embed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. Use this skill when: (1) Producing cell embeddings from an AnnData for clustering/integration, (2) Zero-shot or fine-tuned cell-type annotation, (3) Gene-level representation for perturbation/GRN tasks. For probabilistic single-cell models (scVI etc.), use the scvi-tools library.
Instalare
npx skills add aipoch/open-science --skill scgpt -a claude-code
Se instalează în .claude/skills/scgpt/ · Fiecare comandă descarcă skill-ul direct de pe GitHub cu utilitarul open source skills.
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