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This research advances quantum sensing by solving the critical calibration challenge of random nanodiamond orientations, enabling simultaneous extraction of local magnetic fields and crystallographic axes. By establishing a four-bias-field protocol validated across bulk and single-particle scenarios, the study removes a major barrier to deploying NV centers for high-fidelity biomedical imaging and complex environment sensing.
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Simultaneous Determination of Local Magnetic Fields and Sensor Orientation with Nitrogen-Vacancy Centers in Nanodiamond

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arXiv:2507.05366v2 Announce Type: replace Abstract: Nitrogen-vacancy (NV) centers in nanodiamonds have emerged as a promising quantum sensing platform for biomedical imaging applications, yet random orientations of individual particles present significant challenges in large-scale sensor calibration. In this study, we demonstrate a novel approach to simultaneously determine each particle's crystallographic axes and the surrounding local vector magnetic field. Specifically, a minimum of four distinct bias fields is required to unambiguously extract both the orientation and the local field. We validate our method experimentally using NV centers in two scenarios: (1) in a bulk diamond with known crystal orientation as a proof of concept, and (2) on various single nanodiamonds to mimic real-world applications. Our work represents a crucial step towards unlocking the full potential of nanodiamonds for advanced applications such as in-situ biomedical imaging and nanoscale sensing in complex environments.

Abstract:Nitrogen-vacancy (NV) centers in nanodiamonds have emerged as a promising quantum sensing platform for biomedical imaging applications, yet random orientations of individual particles present significant challenges in large-scale sensor calibration. In this study, we demonstrate a novel approach to simultaneously determine each particle's crystallographic axes and the surrounding local vector magnetic field. Specifically, a minimum of four distinct bias fields is required to unambiguously extract both the orientation and the local field. We validate our method experimentally using NV centers in two scenarios: (1) in a bulk diamond with known crystal orientation as a proof of concept, and (2) on various single nanodiamonds to mimic real-world applications. Our work represents a crucial step towards unlocking the full potential of nanodiamonds for advanced applications such as in-situ biomedical imaging and nanoscale sensing in complex environments.

Main text: 8 pages and 4 figures. Supplemental Material: 14 pages, 9 figures, and 2 tables

Quantum Physics (quant-ph); Biological Physics (physics.bio-ph)

arXiv:2507.05366 [quant-ph]

(or arXiv:2507.05366v2 [quant-ph] for this version)

https://doi.org/10.48550/arXiv.2507.05366 Focus to learn more arXiv-issued DOI via DataCite

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