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This paper presents a novel statistical framework for fusing randomized controlled trials with large observational datasets to improve the precision of treatment effect estimation without introducing bias. By developing specific estimators like AIPW-Fusion and DR-Fusion, it addresses a critical gap in leveraging massive data while maintaining the rigorous standards required for causal inference in machine learning applications.
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Prediction-Powered Data Fusion for Treatment Effect Estimation

arXiv2 min de cititArticolul și perspectiva sunt în engleză.

arXiv:2610.12332v1 Announce Type: cross Abstract: Randomized controlled trials (RCTs) identify treatment effects without confounding but are often small, whereas observational studies (OBS) are large but may be confounded. Many estimators combining a small RCT with a large OBS have been developed for the average treatment effect (ATE) and the conditional ATE (CATE). However, existing ATE estimators either make assumptions on the OBS or do not borrow enough power from them. The CATE has been studied less than the ATE. Existing CATE methods either assume the OBS are unconfounded, rely on a model of the confounding function, or accept bias in exchange for lower variance. We therefore propose a framework that, without special assumptions on the OBS, fuses the OBS and the RCT by preserving the unbiasedness of RCT-based estimation while borrowing power from the large OBS to boost precision. Applying this principle, we build an ATE estimator, AIPW-Fusion, with closed-form weights and confidence intervals, and two CATE learners, DR-Fusion and R-Fusion. Experiments corroborate our findings.

Abstract:Randomized controlled trials (RCTs) identify treatment effects without confounding but are often small, whereas observational studies (OBS) are large but may be confounded. Many estimators combining a small RCT with a large OBS have been developed for the average treatment effect (ATE) and the conditional ATE (CATE). However, existing ATE estimators either make assumptions on the OBS or do not borrow enough power from them. The CATE has been studied less than the ATE. Existing CATE methods either assume the OBS are unconfounded, rely on a model of the confounding function, or accept bias in exchange for lower variance. We therefore propose a framework that, without special assumptions on the OBS, fuses the OBS and the RCT by preserving the unbiasedness of RCT-based estimation while borrowing power from the large OBS to boost precision. Applying this principle, we build an ATE estimator, AIPW-Fusion, with closed-form weights and confidence intervals, and two CATE learners, DR-Fusion and R-Fusion. Experiments corroborate our findings.

35 pages. Code: this https URL

Machine Learning (stat.ML); Artificial Intelligence (cs.AI); Machine Learning (cs.LG); Methodology (stat.ME)

arXiv:2610.12332 [stat.ML]

(or arXiv:2610.12332v1 [stat.ML] for this version)

https://doi.org/10.48550/arXiv.2610.12332 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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