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This paper introduces PILOT, a novel framework enhancing biomedical entity linking through neighborhood-aware retrieval and dual reranking to resolve ambiguities in clinical text normalization. By integrating ontological structures from both queries and knowledge bases, the method achieves state-of-the-art performance across five benchmarks while maintaining inference efficiency for large-scale information extraction tasks.
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Neighborhood-Aware Dual Biomedical Entity Linking

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arXiv:2608.04144v1 Announce Type: cross Abstract: Biomedical entity linking grounds mentions in clinical and scientific text to entities in a curated knowledge base (KB) with ontological structure, which supports downstream applications such as literature-scale information extraction and patient-record normalization. The task has several challenges at once: the KB contains large numbers of entities, mentions are often ambiguous, and gold labels follow annotation conventions specific to each corpus. To address these challenges, we propose PILOT, a three-stage framework made up of neighborhood-aware retrieval, dual reranking, and score fusion. The retriever injects ontological structure from both the query and KB side, by reformulating mentions and pooling entity embeddings. The retrieved pool is then scored from two complementary views, one over surface forms and one over context, and fused together. PILOT achieves the state of the art on average across five widely-used benchmarks and remains efficient at inference.

Abstract:Biomedical entity linking grounds mentions in clinical and scientific text to entities in a curated knowledge base (KB) with ontological structure, which supports downstream applications such as literature-scale information extraction and patient-record normalization. The task has several challenges at once: the KB contains large numbers of entities, mentions are often ambiguous, and gold labels follow annotation conventions specific to each corpus. To address these challenges, we propose PILOT, a three-stage framework made up of neighborhood-aware retrieval, dual reranking, and score fusion. The retriever injects ontological structure from both the query and KB side, by reformulating mentions and pooling entity embeddings. The retrieved pool is then scored from two complementary views, one over surface forms and one over context, and fused together. PILOT achieves the state of the art on average across five widely-used benchmarks and remains efficient at inference.

Information Retrieval (cs.IR); Computation and Language (cs.CL); Machine Learning (cs.LG)

arXiv:2608.04144 [cs.IR]

(or arXiv:2608.04144v1 [cs.IR] for this version)

https://doi.org/10.48550/arXiv.2608.04144 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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