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This research addresses a critical barrier to deploying AI respiratory classifiers in real-world settings by tackling the entanglement of stethoscope artifacts and actual disease signals. The proposed BTS-CAFE framework leverages causality-inspired interventions and counterfactual augmentation within a federated learning setup to create device-invariant decision boundaries, significantly improving out-of-distribution performance on unseen hardware. For practitioners in medical AI, this work offers a robust methodological path toward generalizable models that are not biased by specific recording equipment or demographic shortcuts.
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Mitigating Stethoscope-Induced Shortcuts in Respiratory Sound Classification under Federated Domain Generalization with Causality-Inspired Interventions

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arXiv:2605.29862v2 Announce Type: replace-cross Abstract: AI-driven respiratory sound classification (RSC) is promising for automated pulmonary disease detection, yet multi-site deployment is hindered by inter-stethoscope variability. We introduce a federated domain generalization (FedDG) formulation for RSC in which clients hold recordings from different stethoscopes and the model is evaluated on an unseen device. Our empirical analysis shows that stethoscope-induced style and disease-relevant content are partially entangled, making deterministic style removal unreliable. In response, we propose BTS-CAFE, a framework combining (i) causality-inspired device-style interventions with constraints designed to limit content distortion, (ii) counterfactual metadata augmentation to relieve device and demographic shortcuts, and (iii) gradient alignment to promote device-invariant decision boundaries across clients. Built on BTS with CLAP, a multimodal language-audio pretraining model, BTS-CAFE improves the out-of-distribution ICBHI Score by 3.69 points on average over five held-out devices relative to its backbone, and outperforms conventional data augmentation and federated learning baselines in simulated device leave-out evaluations on the ICBHI and SPRSound datasets.

Abstract:AI-driven respiratory sound classification (RSC) is promising for automated pulmonary disease detection, yet multi-site deployment is hindered by inter-stethoscope variability. We introduce a federated domain generalization (FedDG) formulation for RSC in which clients hold recordings from different stethoscopes and the model is evaluated on an unseen device. Our empirical analysis shows that stethoscope-induced style and disease-relevant content are partially entangled, making deterministic style removal unreliable. In response, we propose BTS-CAFE, a framework combining (i) causality-inspired device-style interventions with constraints designed to limit content distortion, (ii) counterfactual metadata augmentation to relieve device and demographic shortcuts, and (iii) gradient alignment to promote device-invariant decision boundaries across clients. Built on BTS with CLAP, a multimodal language-audio pretraining model, BTS-CAFE improves the out-of-distribution ICBHI Score by 3.69 points on average over five held-out devices relative to its backbone, and outperforms conventional data augmentation and federated learning baselines in simulated device leave-out evaluations on the ICBHI and SPRSound datasets.

Audio and Speech Processing (eess.AS); Artificial Intelligence (cs.AI); Sound (cs.SD)

arXiv:2605.29862 [eess.AS]

(or arXiv:2605.29862v2 [eess.AS] for this version)

https://doi.org/10.48550/arXiv.2605.29862 Focus to learn more arXiv-issued DOI via DataCite

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