InfiMed2: A Generalist Medical Multimodal Foundation Model from Contextual Evidence and Stability-Aware Supervision

arXiv:2609.34798v1 Announce Type: new Abstract: Recent medical multimodal models have benefited from larger corpora, broader modality coverage, and stronger reasoning-oriented training, yet effective data design across continued pretraining (CPT) and post-training remains challenging. Medical sources vary substantially in structure, granularity, and information density, and their utility shifts as training progresses from broad knowledge acquisition to late-stage consolidation. Meanwhile, post-training is often dominated by short-form visual question answering, providing limited supervision for informative and answer-consistent explanations. We introduce InfiMed2, a family of 4B and 27B generalist medical multimodal foundation models built around stage-aware data design. We curate a 55.68B-token corpus that combines broad clinical knowledge with context-rich biomedical visual evidence through source-specific processing. Our CPT pipeline first adapts the vision encoder, then builds broad medical knowledge, and finally transitions to an evidence-focused data mixture during learning-rate decay. For supervised fine-tuning (SFT), we regenerate visual question-answering responses using answer stability, answer-masked reconstruction, and correctness-constrained selection to produce more informative and answer-consistent supervision. The 4B model is further optimized with reinforcement learning with verifiable rewards (RLVR). Across five medical multimodal benchmarks, InfiMed2-4B achieves 66.73% mean accuracy after RLVR, surpassing the larger Qwen3.5-9B, while InfiMed2-27B reaches 73.72%, the highest among the evaluated open-weight models.

Abstract:Recent medical multimodal models have benefited from larger corpora, broader modality coverage, and stronger reasoning-oriented training, yet effective data design across continued pretraining (CPT) and post-training remains challenging. Medical sources vary substantially in structure, granularity, and information density, and their utility shifts as training progresses from broad knowledge acquisition to late-stage consolidation. Meanwhile, post-training is often dominated by short-form visual question answering, providing limited supervision for informative and answer-consistent explanations. We introduce InfiMed2, a family of 4B and 27B generalist medical multimodal foundation models built around stage-aware data design. We curate a 55.68B-token corpus that combines broad clinical knowledge with context-rich biomedical visual evidence through source-specific processing. Our CPT pipeline first adapts the vision encoder, then builds broad medical knowledge, and finally transitions to an evidence-focused data mixture during learning-rate decay. For supervised fine-tuning (SFT), we regenerate visual question-answering responses using answer stability, answer-masked reconstruction, and correctness-constrained selection to produce more informative and answer-consistent supervision. The 4B model is further optimized with reinforcement learning with verifiable rewards (RLVR). Across five medical multimodal benchmarks, InfiMed2-4B achieves 66.73% mean accuracy after RLVR, surpassing the larger Qwen3.5-9B, while InfiMed2-27B reaches 73.72%, the highest among the evaluated open-weight models.

Computation and Language (cs.CL); Computer Vision and Pattern Recognition (cs.CV)

arXiv:2609.34798 [cs.CL]

(or arXiv:2609.34798v1 [cs.CL] for this version)

https://doi.org/10.48550/arXiv.2609.34798 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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InfiMed2: A Generalist Medical Multimodal Foundation Model from Contextual Evidence and Stability-Aware Supervision

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