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This paper is a research preprint on training a small LLM agent with reinforcement learning to call tools that expose patient data groups, using a gradient-boosted tree as the teacher. It reports that a 4B model matches or beats conventional ML baselines on three clinical prediction tasks, but these are preprint results on specific benchmarks, not clinical validation. For AI readers, the useful signal is the diagnosis of LLM failures (poor feature selection and weak numerical reasoning) and the reverse-curriculum approach for internalizing skills.
Incentivizing Tool-Use Reinforcement Learning for Post-Arrival Emergency Care Prediction
arXiv:2610.21449v1 Announce Type: new Abstract: Large language models (LLMs) can reason over both structured measurements and free-text records, which makes them attractive for emergency department (ED) prediction. However, most existing LLMs still fall short of conventional ML methods like trees on EHR-based prediction tasks. Our controlled analysis traces this gap to two weaknesses: LLMs do not select informative features, and they misjudge what numerical values imply for risk even when given the right features. We propose TIR-EC, a tool-integrated reinforcement learning framework that addresses both. TIR-EC exposes EHR feature groups as tools the LLM can call. It trains the LLM with rewards from a gradient-boosted tree teacher, which provides a reference set of informative tools and a graded risk target. TIR-EC also distills task-specific clinical skills into the model weights through a reverse curriculum that gradually removes the skills from the prompt during RL process. Evaluation on three clinical prediction tasks shows that our 4B agent achieves the highest macro F1 of all compared models, outperforms conventional ML baselines, and is competitive with much larger frontier LLMs. Further analysis shows that TIR-EC selects more useful evidence with fewer tool calls and combines measurements more effectively.
Abstract:Large language models (LLMs) can reason over both structured measurements and free-text records, which makes them attractive for emergency department (ED) prediction. However, most existing LLMs still fall short of conventional ML methods like trees on EHR-based prediction tasks. Our controlled analysis traces this gap to two weaknesses: LLMs do not select informative features, and they misjudge what numerical values imply for risk even when given the right features. We propose TIR-EC, a tool-integrated reinforcement learning framework that addresses both. TIR-EC exposes EHR feature groups as tools the LLM can call. It trains the LLM with rewards from a gradient-boosted tree teacher, which provides a reference set of informative tools and a graded risk target. TIR-EC also distills task-specific clinical skills into the model weights through a reverse curriculum that gradually removes the skills from the prompt during RL process. Evaluation on three clinical prediction tasks shows that our 4B agent achieves the highest macro F1 of all compared models, outperforms conventional ML baselines, and is competitive with much larger frontier LLMs. Further analysis shows that TIR-EC selects more useful evidence with fewer tool calls and combines measurements more effectively.
Artificial Intelligence (cs.AI)
arXiv:2610.21449 [cs.AI]
(or arXiv:2610.21449v1 [cs.AI] for this version)
https://doi.org/10.48550/arXiv.2610.21449 Focus to learn more arXiv-issued DOI via DataCite (pending registration)
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