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ExpertoRhythm introduces a morphology-aware learning objective within an attention-enhanced 1D U-Net to reconstruct arterial blood pressure waveforms from single-channel PPG signals. By integrating range-weighted loss functions, the model achieves clinically significant accuracy that outperforms standard MSE approaches across diverse pressure ranges up to 200 mmHg. This work advances the feasibility of continuous, cuffless blood pressure monitoring for wearable health applications through specialized deep learning architectures.
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ExpertoRhythm: Morphology-Aware Learning for Waveform Reconstruction and Cuffless Blood Pressure Estimation from Single-Channel PPG

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arXiv:2609.34146v1 Announce Type: new Abstract: Continuous cuffless blood pressure (BP) monitoring from photoplethysmography (PPG) has strong potential for wearable health and telemonitoring, but accurate estimation remains difficult because PPG-to-BP mapping must preserve subtle waveform morphology and pressure-range-dependent dynamics. We introduce ExpertoRhythm, an attention-enhanced 1D U-Net that reconstructs the arterial blood pressure (ABP) waveform from a single-channel PPG signal and derives systolic and diastolic BP directly from the reconstructed waveform. The central contribution is a composite morphology-aware learning objective that integrates range-weighted SmoothL1 reconstruction with a window-range regularizer to emphasize high-dynamic BP segments and reduce amplitude under/over-shoot. On the UCI cuff-less BP dataset with 942 subjects, ExpertoRhythm achieves 2.46/1.46 mmHg MAE for systolic/diastolic BP (SBP/DBP), while obtaining a 30.4% average relative error reduction over pure MSE across waveform reconstruction and BP estimation metrics. Clinical-style evaluation further demonstrates low bias and strong agreement across the BP range, including high-pressure windows up to 200 mmHg, satisfying AAMI criteria and achieving BHS Grade A. These results suggest that morphology-aware waveform reconstruction from a single PPG channel can provide an accurate and practical pathway toward continuous cuffless BP monitoring in wearable and remote-care settings.

Abstract:Continuous cuffless blood pressure (BP) monitoring from photoplethysmography (PPG) has strong potential for wearable health and telemonitoring, but accurate estimation remains difficult because PPG-to-BP mapping must preserve subtle waveform morphology and pressure-range-dependent dynamics. We introduce ExpertoRhythm, an attention-enhanced 1D U-Net that reconstructs the arterial blood pressure (ABP) waveform from a single-channel PPG signal and derives systolic and diastolic BP directly from the reconstructed waveform. The central contribution is a composite morphology-aware learning objective that integrates range-weighted SmoothL1 reconstruction with a window-range regularizer to emphasize high-dynamic BP segments and reduce amplitude under/over-shoot. On the UCI cuff-less BP dataset with 942 subjects, ExpertoRhythm achieves 2.46/1.46 mmHg MAE for systolic/diastolic BP (SBP/DBP), while obtaining a 30.4% average relative error reduction over pure MSE across waveform reconstruction and BP estimation metrics. Clinical-style evaluation further demonstrates low bias and strong agreement across the BP range, including high-pressure windows up to 200 mmHg, satisfying AAMI criteria and achieving BHS Grade A. These results suggest that morphology-aware waveform reconstruction from a single PPG channel can provide an accurate and practical pathway toward continuous cuffless BP monitoring in wearable and remote-care settings.

Machine Learning (cs.LG)

arXiv:2609.34146 [cs.LG]

(or arXiv:2609.34146v1 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2609.34146 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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