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This research critically examines covariate balance diagnostics in offline reinforcement learning, revealing significant risks of bias and model misspecification in current treatment recommendation studies. The findings suggest that existing metrics are insufficient to guarantee statistical robustness, necessitating new methodological approaches for long-horizon decision processes.
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Evaluating covariate balance for long time horizon Markov decision processes

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arXiv:2607.15080v2 Announce Type: replace Abstract: This article explores the application of covariate balance diagnostics for detecting the presence of hidden confounding/model miss-specification in studies applying offline reinforcement learning (RL) to deriving optimal treatment recommendations. The results demonstrate that, either there is a high risk of bias within existing offline RL studies for treatment recommendations and/or, existing covariate balance metrics are not sufficient to assess such studies. Regardless, existing offline RL studies cannot be concluded as being statistically robust. The conclusions propose future research directions for obtaining more methodologically robust applications of offline RL to treatment recommendation problems.

Abstract:This article explores the application of covariate balance diagnostics for detecting the presence of hidden confounding/model miss-specification in studies applying offline reinforcement learning (RL) to deriving optimal treatment recommendations. The results demonstrate that, either there is a high risk of bias within existing offline RL studies for treatment recommendations and/or, existing covariate balance metrics are not sufficient to assess such studies. Regardless, existing offline RL studies cannot be concluded as being statistically robust. The conclusions propose future research directions for obtaining more methodologically robust applications of offline RL to treatment recommendation problems.

Machine Learning (cs.LG)

arXiv:2607.15080 [cs.LG]

(or arXiv:2607.15080v2 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2607.15080 Focus to learn more arXiv-issued DOI via DataCite

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