EHR-RobustGym: Benchmarking and Training Agents for Robust Clinical Reasoning

arXiv:2609.39371v1 Announce Type: new Abstract: In hospital workflows, electronic health records (EHRs) are often noisy, and may not contain the evidence needed to confirm events or measurements referenced in a clinical query. Even when database retrieval succeeds, clinical agents can overlook such discrepancies and return plausible but unsupported answers. We introduce EHR-RobustGym, a scalable and interactive environment for evaluating and training robust clinical agents grounded in noisy EHRs. Built on MIMIC-IV hospital records (365K patients, 31 tables, and over 500M records), EHR-RobustGym comprises 5,486 Clean-Noise pairs spanning six clinical intents and both patient-level and population-level queries. The pairs test robustness to Record-level, Value-level, and Query-level noise, while interactive SQL/Python execution and outcome verification support trajectory collection and training. Evaluating multiple LLMs reveals substantial robustness gaps: average task success across proprietary and large-scale open-weight models drops from 62.2% on Clean questions to 37.9% on Noise questions. At k=4, pass^k consistency falls below 50% for most evaluated models, exposing instability in clinical task completion. Supervised fine-tuning and reinforcement learning in EHR-RobustGym improve performance, with gains generalizing to five external EHR benchmarks. Together, these results position EHR-RobustGym as a testbed for evaluating and improving the evidence-grounded robustness of clinical agents.

Abstract:In hospital workflows, electronic health records (EHRs) are often noisy, and may not contain the evidence needed to confirm events or measurements referenced in a clinical query. Even when database retrieval succeeds, clinical agents can overlook such discrepancies and return plausible but unsupported answers. We introduce EHR-RobustGym, a scalable and interactive environment for evaluating and training robust clinical agents grounded in noisy EHRs. Built on MIMIC-IV hospital records (365K patients, 31 tables, and over 500M records), EHR-RobustGym comprises 5,486 Clean-Noise pairs spanning six clinical intents and both patient-level and population-level queries. The pairs test robustness to Record-level, Value-level, and Query-level noise, while interactive SQL/Python execution and outcome verification support trajectory collection and training. Evaluating multiple LLMs reveals substantial robustness gaps: average task success across proprietary and large-scale open-weight models drops from 62.2% on Clean questions to 37.9% on Noise questions. At k=4, pass^k consistency falls below 50% for most evaluated models, exposing instability in clinical task completion. Supervised fine-tuning and reinforcement learning in EHR-RobustGym improve performance, with gains generalizing to five external EHR benchmarks. Together, these results position EHR-RobustGym as a testbed for evaluating and improving the evidence-grounded robustness of clinical agents.

Artificial Intelligence (cs.AI); Machine Learning (cs.LG)

arXiv:2609.39371 [cs.AI]

(or arXiv:2609.39371v1 [cs.AI] for this version)

https://doi.org/10.48550/arXiv.2609.39371 Focus to learn more arXiv-issued DOI via DataCite (pending registration)

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EHR-RobustGym: Benchmarking and Training Agents for Robust Clinical Reasoning

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