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This research reveals a critical trade-off in scientific AI, demonstrating that fine-tuning models on domain-specific data can degrade factual reliability rather than improve it. The study highlights how these specialized models become internally less confident while appearing more assertive, complicating trust in high-stakes scientific applications. Consequently, the field must prioritize developing robust verification infrastructure over relying solely on domain adaptation to mitigate hallucinations.
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Does Finetuning with Scientific Data Increase Hallucinations? A Multi-domain Factuality Evaluation of LLMs

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arXiv:2606.21359v2 Announce Type: replace Abstract: Large language models (LLMs) are increasingly used to communicate and explain scientific concepts, yet their tendency to hallucinate poses significant risks in this high stakes use-case. Prior scientific hallucination evaluation work remains largely restricted to the biomedical domain, treats hallucination as a binary task, and has not examined the growing family of scientifically fine-tuned LLMs. We address these gaps with SciFactCheck, a benchmark of 2,500 prompts across five scientific domains, paired with a modular evaluation framework targeting three factuality hallucination types: unverifiability, overclaim, and attribution. Using a controlled minimal-pairing design, we evaluate 18 LLMs by comparing each scientifically fine-tuned model against its general-purpose base. Our results indicate that 1. Scientifically fine-tuned models exhibit degraded factual reliability across all hallucination types and scientific domains, and 2. Fine-tuned models are internally less confident yet linguistically more assertive. A human pilot study further reveals that current fact-checking tools show only modest agreement with expert judgments on scientific content, and that defining scientifically check-worthy claims remains contested even among human annotators. Our findings fundamentally challenge current methods of domain-specific fine-tuning for factuality and call for developing improved verification infrastructure for scientific content.

Title:Does Finetuning with Scientific Data Increase Hallucinations? A Multi-domain Factuality Evaluation of LLMs

Abstract:Large language models (LLMs) are increasingly used to communicate and explain scientific concepts, yet their tendency to hallucinate poses significant risks in this high stakes use-case. Prior scientific hallucination evaluation work remains largely restricted to the biomedical domain, treats hallucination as a binary task, and has not examined the growing family of scientifically fine-tuned LLMs. We address these gaps with SciFactCheck, a benchmark of 2,500 prompts across five scientific domains, paired with a modular evaluation framework targeting three factuality hallucination types: unverifiability, overclaim, and attribution. Using a controlled minimal-pairing design, we evaluate 18 LLMs by comparing each scientifically fine-tuned model against its general-purpose base. Our results indicate that 1. Scientifically fine-tuned models exhibit degraded factual reliability across all hallucination types and scientific domains, and 2. Fine-tuned models are internally less confident yet linguistically more assertive. A human pilot study further reveals that current fact-checking tools show only modest agreement with expert judgments on scientific content, and that defining scientifically check-worthy claims remains contested even among human annotators. Our findings fundamentally challenge current methods of domain-specific fine-tuning for factuality and call for developing improved verification infrastructure for scientific content.

Computation and Language (cs.CL)

arXiv:2606.21359 [cs.CL]

(or arXiv:2606.21359v2 [cs.CL] for this version)

https://doi.org/10.48550/arXiv.2606.21359 Focus to learn more arXiv-issued DOI via DataCite

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