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This study demonstrates the practical utility of LLM coding agents in advancing mathematical research within coding theory, specifically by automating search algorithms for DNA barcode-like structures. The authors highlight critical lessons on error propagation and verification protocols when delegating complex symbolic reasoning to AI agents.
Coding Agents for Coding Theory
arXiv:2609.39081v1 Announce Type: cross Abstract: We spent five weeks using an LLM coding agent on open problems in coding theory: finding large sets of four-letter words, such as DNA barcodes, that stay far apart in edit distance. The agent wrote the verifiers and search code; a human chose the problem and set the verification protocol. Restricting the search to codes with a prescribed symmetry, a classical technique, shrank the problem about fourfold and raised the best known code of length 6 and minimum edit distance 3 from 114 to 120 words ($E_4(6,3) \geq 120$). The same pipeline improved twelve further lower bounds at lengths 6 to 9 and distances 3 to 6. We give the failures equal space. Our own search stopped at 116 and recorded the last symmetry class as topping out at 112; a second agent session, running the same search with a better operator, found the 120. A later verdict that the method did not carry over to length 7 was wrong for the same reason, and an earlier instance cost three weeks. Each time, an intermediate result was written down, never rechecked, and treated as a fact that ruled out further search. Checking final outputs, as our protocol required, does not catch such errors.
Abstract:We spent five weeks using an LLM coding agent on open problems in coding theory: finding large sets of four-letter words, such as DNA barcodes, that stay far apart in edit distance. The agent wrote the verifiers and search code; a human chose the problem and set the verification protocol. Restricting the search to codes with a prescribed symmetry, a classical technique, shrank the problem about fourfold and raised the best known code of length 6 and minimum edit distance 3 from 114 to 120 words ($E_4(6,3) \geq 120$). The same pipeline improved twelve further lower bounds at lengths 6 to 9 and distances 3 to 6. We give the failures equal space. Our own search stopped at 116 and recorded the last symmetry class as topping out at 112; a second agent session, running the same search with a better operator, found the 120. A later verdict that the method did not carry over to length 7 was wrong for the same reason, and an earlier instance cost three weeks. Each time, an intermediate result was written down, never rechecked, and treated as a fact that ruled out further search. Checking final outputs, as our protocol required, does not catch such errors.
Accepted at the 6th Workshop on Mathematical Reasoning and AI (MATH-AI), NeurIPS 2026. 20 pages, 1 figure, 2 tables. Code and data: this https URL
Information Theory (cs.IT); Artificial Intelligence (cs.AI); Machine Learning (cs.LG)
I.2.8; G.2.1; E.4
arXiv:2609.39081 [cs.IT]
(or arXiv:2609.39081v1 [cs.IT] for this version)
https://doi.org/10.48550/arXiv.2609.39081 Focus to learn more arXiv-issued DOI via DataCite (pending registration)
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