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This study provides critical empirical evidence on how natural scientists are adopting pre-trained models to bypass the high costs of training from scratch, marking a significant shift in scientific methodology. By analyzing nearly 18,000 papers, it reveals that adaptation is the dominant reuse pattern and highlights biochemistry as the leading field for integrating these tools into testing stages. This data offers essential insights for researchers evaluating practical deployment strategies and resource allocation across disciplines.
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An Empirical Investigation of Pre-Trained Deep Learning Model Reuse in the Scientific Process

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arXiv:2603.13584v2 Announce Type: replace-cross Abstract: Deep learning has achieved recognition for its impact within natural sciences, yet the prohibitive financial and technical cost of training models from scratch inhibit adoption. Following software engineering community guidance, natural scientists are reusing pre-trained deep learning models (PTMs) to amortize these costs. While prior works recommend PTM reuse patterns, we present the first empirical study of PTM reuse patterns in the natural sciences, quantifying the utilization and impact of PTM reuse within the scientific process across 17,718 peer reviewed, open access papers. Our results show that "Biochemistry, Genetics and Molecular Biology" has outpaced other natural scientific fields in PTM reuse, "adaptation" reuse is the most prevalent PTM reuse pattern identified across all natural science fields, and the "testing" stage of the scientific process has been most impacted by PTM integration.

Abstract:Deep learning has achieved recognition for its impact within natural sciences, yet the prohibitive financial and technical cost of training models from scratch inhibit adoption. Following software engineering community guidance, natural scientists are reusing pre-trained deep learning models (PTMs) to amortize these costs. While prior works recommend PTM reuse patterns, we present the first empirical study of PTM reuse patterns in the natural sciences, quantifying the utilization and impact of PTM reuse within the scientific process across 17,718 peer reviewed, open access papers. Our results show that "Biochemistry, Genetics and Molecular Biology" has outpaced other natural scientific fields in PTM reuse, "adaptation" reuse is the most prevalent PTM reuse pattern identified across all natural science fields, and the "testing" stage of the scientific process has been most impacted by PTM integration.

Software Engineering (cs.SE); Artificial Intelligence (cs.AI)

arXiv:2603.13584 [cs.SE]

(or arXiv:2603.13584v2 [cs.SE] for this version)

https://doi.org/10.48550/arXiv.2603.13584 Focus to learn more arXiv-issued DOI via DataCite

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